PUBLICATIONS

Peer-reviewed Publications

2024

Pratelli, M., Kaimi, A. M., Thaker, A., Jang, H., Li, H. Q., Godavarthi, S. K., Lim, B. K., Spitzer, N. (2024) Drug-induced change in transmitter identity is a shared mechanism generating cognitive deficits. Nature Communication., 26(15):8260.
Wirthlin, M. E., et al. (2024) Vocal learning-associated convergent evolution in mammalian proteins and regulatory elements. Science. 29:383(6690)
Jeong, M., Choi, J. H., Jang, H., Sohn, D. H., Wang, Q., Lee, J., Yao, L., Lee, E. J., Fan, J., Pratelli, M., Wang, E. H., Snyder, C. H., Wang, X., Y., Shin, S., Gittis, A. H., Sung, T. C., Spitzer, N., Lim, B. K. (2024) Viral vector-mediated transgene delivery with novel recombinase systems for targeting neuronal populations defined by multiple features. Neuron., 112(1):56-72.

2023

Hattori, R., Chen, S., You, H., Hattori, M., Choi, J. H., Lim, B. K., Hedrick, N., Jain, A., Yasuda, R., Komiyama, T. (2023) Meta-reinforcement learning via orbitofrontal cortex. Nature Neuroscience., 26(12):2192-2191.
Shin, S.*, In-Jee, You., Jeong, M., Bae. Y., Wang, X., Cawley, M. L., Han, A., Lim, B. K.* (2023) Early adversity promotes binge-like eating habits by remodeling a leptin-responsive lateral hypothalamus–brainstem pathway. Nature Neuroscience. 26(1):79-91

2022

Hedrick, N. G., Lu, Z., Bushong, E., Singhi, S., Nguyen, P., Magaña, Y., Jilani, S., Lim, B. K., Ellisman, M., Komiyama, T. (2022) Learning binds new inputs into functional synaptic clusters via spinogenesis. Nature Neuroscience. 25(6):726-737.

2021

Brain Initiative Cell Census Network (BICCN) team (2021) A multimodal cell census and atlas of mammalian primary motor cortex. Nature 598, 86–102
Munoz-Castaneda, R., et al. (2021) Cellular anatomy of the mouse primary motor cortex. Nature 598, 159-166.
Foster, N. N., Korobkova, L., Garcia, L., Peng, B., Sherafat, Y., Gao, L., Becerra, M., Bowman, I., Azam, S., Lo, D., Guo, L., Khanjani, N., Zhang, B., Stanis, J., Cotter, K., Yamashita, S., Zingg, B., Yang, X. W., Wickersham, I., Zhang, L., Lim, B. K., Hintiryan, H., Dong, H.W. (2021) The mouse cortico-basal ganglia-thalamic network. Nature 598, 188-194.
Jeong, M., Lee, H., Kim, Y., Wang, E. H., Paik, S. B., Lim, B. K.*, Kim, D.* (2021) Interhemispheric Cortico-Cortical pathway for sequential bimanual movements in mice. eNeuro 8(4), doi: 10.1523/ENEURO.0200-21.2021. (* co-corresponding)
Pribiag, H., Shin, S., Wang, E. G., Sun, F., Datta, P., Okamoto, A., Guss, H., Jain, A., Wang, X. Y., De Freitas, B., Honma, P., Pate, S., Lilascharoen, V., Li, Y., Lim, B. K. (2021) Ventral pallidum DRD3 controls accumbal dopamine release and drug seeking. Neuron 109(13):2165-2182.e10. doi: 10.1016/j.neuron.2021.05.002.
McElvain, L. E., Chen, Y., Moore, J. D., Brigidi, G. S., Bloodgood, B. L., Lim, B. K., Costa, R. M., Kleinfeld, D. (2021) Specific populations of basal ganglia output neurons target distinct brain stem areas while collateralizing throughout the diencephalon. Neuron. 109(10):1721-1738.e4. doi: 10.1016/j.neuron.2021.03.017.
Chen, J., Markowitz, J. E., Lilascharoen, V., Taylor, S., Sheurpukdi, P., Keller, J. A., Jensen, J. R., Lim, B. K., Datta, S. R., Stowers, L. (2021) Flexible scaling and persistence of social vocal communication. Nature. https://doi.org/10.1038/s41586-021-03403-8
Cui, Q., Du, X., Chang, I. Y. M., Pamukcu, A., Lilascharoen, V., Berceau, B. L., García, D., Hong, D., Chon, U., Narayanan, A., Kim, Y., Lim, B. K., Chan CS. (2021) Striatal Direct Pathway Targets Npas1+ Pallidal Neurons. J Neurosci 41(18):3966-3987. doi: 10.1523/JNEUROSCI.2306-20.2021.
Lilascharoen, V., Wang. E. H., Do, N., Pate, S. C., Tran, A. N., Wang, X. Y., Park, Y. G., Chung, K., Lim, B. K. (2021) Divergent pallidal pathways underlying distinct Parkinsonian behavioral deficits. Nature Neuroscience 24, 504-515.

2020

Pribiag, H., Lim, B. K. (2020) Thalamic Retrieval of Opioid Memories. Neuron. 23;107(6):992-994. doi: 10.1016/j.neuron.2020.09.006
Yamaguchi, T., Wei, D., Song, S. C., Lim, B. K., Tritsch, N. X., Lin, D. (2020) Parallel pathways from posterior amygdala control sexual and aggressive behaviors. Nature Neuroscience 23, 1111-1124.
Kim, W.S., Jeong, M., Hong, S., Lim, B. K., Park, S. I. (2020) Fully Implantable Low-Power High Frequency Range Optoelectronic Devices for Dual-Channel Modulation in the Brain. Sensors 20,3639.
Abecassis, Z. A.*, Berceau, B. L.*, Win, P. H., Garcia, D., Xenias, H. S., Cui, Q., Pamucku, A., Cherian, S., Hernández, V. M., Chon, U., Lim, B. K., Justice, N. J., Awatramani, R., Kim, Y., Hooks, B. M., Gerfen, C .R., Boca, S. M., Chan, C. S. (2020) Npas1+ -Nkx2.1 + Neurons As an Integral Part of the Cortico-pallido-cortical Loop. J Neurosci, 40(4); 743-768.

2019

Cerniaiskas, I., Winterer, J., de Jong, J. W., Lukacosovich, D., Yang, H., Khan, F., Peck, J., Lilascharoen, V., Lim, B. K., Foldy, C., Lammel, S. (2019) Anatomical, molecular and functional heterogeneity of the lateral habenula defines a distinctive depression subtype. Neuron, 104, 1-17.
Hwang, E. J., Link, T. D., Hu, Y., Lu, S., Wang, E. H., Lilascharoen, V., Aaronson, S., Malinow, R., Lim, B. K., Komiyama, T. (2019) Corticostriatal flow of action selection bias. Neuron,104, 1-126-1140

2018

Park, Y. G., Sohn, C. H., Chen, R., McCue, M., Yun, D. H., Drummond, G. T., Ku, T., Evans, N. B., Oak, H. C., Trieu, W., Choi, H., Jin, X., Lilascharoen, V., Wang, J., Truttmann, M. C., Qi, H. W., Ploegh, H. L., Golub, T. R., Chen, S. C., Frosch, M. P., Kulik, H. J., Lim, B. K., Chung, K. (2018) Protection of tissue physicochemical properties using polyfunctional crosslinkers. Nat Biotechnol. 37, 73-83.
Zutshi, I., Fu, M. L., Lilascharoen, V., Leutgeb, J. K., Lim, B. K., Leutgeb, S. (2018) Recurrent circuits within medial entorhinal cortex superficial layers support grid cell firing. Nat Commun. 12;9(1):3701.
Keller, J., Chen, J., Simpson, S., Wang, E. H., Lilascharoen, V., Lim, B. K., Stowers, L. (2018) Voluntary urination control by brainstem neurons that relax the urethral sphincter. Nature Neuroscience, 21(9):1229-1238
Atlan, G., Terem, A., Peretz-Rivlin, N., Sehrawat, K., Gonzales, B. J., Pozner, G., Tasala, G., Goll, Y., Refaeli, R., Zviran, O., Lim, B. K., Groysman, M., Goshen, I., Mizrahi, A., Nelken, I., Citri, A. (2018) The claustrum supports resilience to distraction, Current Biology, 28(17):2752-2762.
Barrientos, C., Knowland, D., Wu, MMJ., Lilascharoen, V., Huang, K. W., Malenka, R. C., Lim, B. K. (2018) Cocaine-induced structural plasticity in input regions to distinct cell types in nucleus accumbens. Biological Psychiatry 84(12):893-904.
Shin, S., Pribiag, H., Lilascharoen, V., Knowland, D., Wang, X., Lim, B. K. (2018) Drd3 signaling in the lateral septum mediates early life stress-induced social dysfunction. Neuron, 97(1):195-208.
Knowland, D., Lim, B. K. (2018) Circuit-based frameworks of depressive behaviors: The role of reward circuitry and beyond. Pharmacol Biochem Behav. S0091-3057(17)30452-5 Review

2017

Liu, J., Conde, K., Zhang, P., Lilascharoen, V., Xu, Z., Lim, B. K., Seeley, R. J., Zhu, J. J., Scott, M. M., Pang, Z.P. (2017) Enhanced AMPA Receptor Trafficking Mediates the Anorexigenic Effect of Endogenous Glucagon-like Peptide-1 in the Paraventricular Hypothalamus. Neuron. 96(4):897-909.
Knowland, D., Lilascharoen, V., Pacia, C. C., Shin, D., Wang, E., Lim, B. K. (2017) Distinct ventral pallidal neural populations mediate separate symptoms of depression. Cell 170(2):284-297
Yoo, J. H., Zell, V., Wu, J., Punta, C., Ramajayam, N., Shen, X., Faget, L., Lilascharoen, V., Lim, B. K., Hnasko, T. S. (2017) Activation of Pedunculopontine Glutamate Neurons Is Reinforcing. J Neurosci. 37(1):38-46.

Previous years

Rothwell, P. E., Hayton, S. J., Sun, G. L., Fuccillo, M. V., Lim, B. K., Malenka, R. C. (2015) Input- and Output-Specific Regulation of Serial Order Performance by Corticostriatal Circuits. Neuron 88(2):345-356.
Schwartz, N., Temkin, P., Jurado, S., Lim, B. K., Polepalli, J. S., Malenka, R. C. (2014) Decreased motivation during chronic pain requires plasticity in the nucleus accumbens core. Science 345(6196) 535-542.
Rothwell, P. E, Fuccillo, M. V., Maxeiner, S., Hayton, S. J., Lim, B. K., Malenka, R. C., Südhof, T. C. (2014) Autism-associated Neuroligin-3 mutations impair striatal circuits underlying repetitive motor routins. Cell. 158(1):198-212.
Lammel, S.*, Lim, B. K.*, Malenka, R. C. (2014) Reward and aversion in a heterogenous midbrain dopamine system. Neuropharmacology. 76 Pt. B: 351-9 (* equal contribution)
Kim, S. Y., Adhikari, A., Lee, S. Y., Marshel, J. H., Kim, C. K., Mallory, C. S., Lo, M., Pak, S., Mattis, J., Lim, B. K., Malenka, R. C., Warden, M. R., Neve, R., Tye, K. M., Deisseroth, K. (2013) Diverging neural pathways assemble a behavioural state from separable features in anxiety. Nature. 496(7444): 219-223.
Lammel, S.*, Lim, B. K.*, Ran, C., Huang, K. W., Tye, K., Deisseroth, K., Malenka, R. C. (2012) Input-specific control of reward and aversion in the ventral tegmental area. Nature (Article) 491(7423): 212-217 (* equal contribution)
Lim, B. K., Huang, K. W., Grueter, B. A., Rothwell, P. E., Malenka, R. C. (2012) Anhedonia requires MC4R-mediated synaptic adaptation in nucleus accumbens. Nature (Article) 487(7406): 183-189.
Shelly, M., Cancedda, L., Lim, B. K., Popescu, A. T., Cheng, P. L., Gao, H., Poo, M. M. (2011) Semaphorin3A regulates neuronal polarization by suppressing axon formation and promoting dendrite growth. Neuron. 71(3):433-446.
Lu, H., Cheng, P. L., Lim, B. K., Khoshnevisrad, N., Poo, M. M. (2010) Elevated BDNF expression after cocaine withdrawal facilitates LTP in medial prefrontal cortex by suppressing GABA inhibition. Neuron. 67(5):821-833.
Lim, B. K., Cho, S. J., Sumbre, G., Poo, M. M. (2010) Region-specific contribution of ephrin-B and Wnt signaling to receptive field plasticity in developing optic tectum. Neuron. 65(6):899-911.
Shelly, M.*, Lim, B. K.*, Cancedda, L., Heilshorn, S. C., Gao, H., Poo, M. M. (2010) Local and long-range reciprocal regulation of cAMP and cGMP in axon/dendrite formation. Science. (Article) 327(5965):547-552. (* equal contribution)
Lu, H., Lim, B., Poo, M. M. (2009) Cocaine exposure in utero alters synaptic plasticity in the medial prefrontal cortex of postnatal rats. J Neurosci. 29(40):12664-12674.
Lim, B. K., Matsuda, N., Poo, M. M. (2008) Ephrin-B reverse signaling promotes structural and functional synaptic maturation in vivo. Nat Neurosci. 11(2):160-169.
Rho, S. H., Park, H. H., Kang, G. B., Im, Y. J., Kang, M. S., Lim, B. K., Seong, I. S., Seol, J., Chung, C. H., Wang, J., Eom, S. H. (2008) Crystal structure of Bacillus subtilis CodW, a noncanonical HslV-like peptidase with an impaired catalytic apparatus. Proteins. 71(2):1020-1026.
Shin, O. H., Maximov, A., Lim, B. K., Rizo, J., Südhof, T. C. (2004) Unexpected Ca2+-binding properties of synaptotagmin 9. Proc Natl Acad Sci U S A. 101(8):2554-2559.
Kang, M. S., Kim, S. R., Kwack, P., Lim, B. K., Ahn, S. W., Rho, Y. M., Seong, I. S., Park, S. C., Eom, S. H., Cheong, G. W., Chung, C. H. (2003) Molecular architecture of the ATP-dependent CodWX protease having an N-terminal serine active site. EMBO J. 22(12):2893-2902.
Kang, M. S., Lim, B. K., Seong, I. S., Seol, J. H., Tanahashi, N., Tanaka, K., Chung, C. H.(2001) The ATP-dependent CodWX (HslVU) protease in Bacillus subtilis is an N-terminal serine protease. EMBO J. 20(4):734-742.